In this booklet, the recommended antibiotics for management of common infections are included and divided into two categories, first choice antibiotics and alternative. It will indeed assist clinicians and promote appropriate antibiotic therapy and prophylaxis. Three years (2019-22) data of common microorganisms and antimicrobial susceptibility pattern, of Microbiology unit, Pathology Department, Bahria International Hospital, Lahore, is incorporated. Chapter antibiotic stewardship with role of clinicians, Microbiologist, pharmacists, nursing, housekeeping, and administrators is added. Pharmacist role in monitoring antibiotics usage for In-patients, OPD and ER is specially designed.